Clinical features and management of primary biliary cirrhosis

Table 3 Parameters independently associated with bad prognosis in different prognostic models based on a single point observation[16113119121–123]

Parameters	Yale	European	Mayo	Glasgow	Oslo	London
Increase in serum bilirubin	+	+	+	+	+	+
Decrease in serum albumin		+	+			+
Increase in PT (INR)			+
Advanced age	+	+	+	+		+
Hepatomegaly	+					+
Ascites, fluid retention			+	+		+
Esophageal varices						+
Gastrointestinal bleeding				+	+
Cirrhosis	+	+		+		+
Cholestatic picture at histology		+		+
Mallory bodies				+