Control of gallbladder contractions by cholecystokinin through cholecystokinin-A receptors on gallbladder interstitial cells of cajal

Figure 3 Effect of atropine and TTX on CCK-8 induced contraction of gallbladder muscle strips. The addition of atropine (10^-6 mol/L) or TTX (3 × 10^-7 mol/L) to the medium had no effect on the control dose-response curve for CCK-8. Each value is the mean ± SE obtained in 5 observations and observed at 10^-10, 10^-9, 10^-8, 10^-7, 10^-6 mol/L. Series 1: CCK-8+TTX; Series 2: CCK-8+atropine; Series 3: CCK-8 alone.