Clinicopathologic characteristics of intrahepatic cholangiocarcinoma in patients with positive serum a-fetoprotein

Table 1 Clinical features of ICC patients with positive AFP

	AFP
	+ (n = 32)	- (n = 99)	P value
Gender (M/F)	24/8	66/33	NS
Age (yr)	48.7 ± 11.7	54.5 ± 9.9	0.007
HBsAg + (%)	25 (78.1)	38 (38.3)	0.000
Anti-HCV + (%)	0	1 (0.01)	NS
CA19-9 (> 37 U/mL) (%)	10 (31.4)	58 (58.6)	0.007
TBIL (> 17.1 &mgr;mol/L) (%)	17 (53.1)	39 (39.4)	NS
ALT (> 40 IU/L) (%)	16 (50.0)	26 (26.3)	0.012
AST (> 40 IU/L) (%)	14 (43.8)	23 (23.2)	0.025

NS: Not significant; M: Male; F: Female; HBsAg: Hepatitis B surface antigen; HCV: Hepatitis C virus antibody; TBIL: Total bilirubin; AST: Aspartate transaminase; ALT: Alanine transaminase.