Factors influencing a low rate of hepatitis C viral RNA clearance in heroin users from Southern China

Table 2 Factors associated with hepatitis C viral clearance among 347 consecutively HCV antibody positive heroin users from Guangxi Zhuang Autonomous Region, China

	Number	Univariate	Final multivariate model
Factor	(% clearance)	Adjusted OR (95% CI)	Adjusted OR (95% CI)	P
Age (yr)
≤ 25	125 (13.6)	1.0	1.0
> 25	222 (5.9)	0.472 (0.221-1.006)	0.400 (0.176-0.909)	0.029
HIV Ab status
Negative	257 (10.5)	1.0	1.0
Positive	90 (3.3)	0.294 (0.087-0.993)	0.256 (0.071-0.924)	0.038
HBsAg status
Negative	301 (5.3)	1.0	1.0
Positive	46 (30.4)	7.793 (3.484-17.430)	8.436 (3.646-19.520)	< 0.0001
HBsAb status
Negative	199 (12.1)	1.0
Positive	148 (4.1)	0.308 (0.123-0.744)
Gender
Male	334 (8.1)	1.0
Female	13 (23.1)	3.411 (0.885-13.143)
Location
Binyang	220 (9.1)	1.0
Pingxiang	127 (7.9)	0.855 (0.387-1.888)
Ethnicity
Zhuang minority	115 (8.7)	1.0
Han	232 (8.6)	0.991 (0.448-2.192 )
Injection drug use
Yes	323 (9.0)	1.0
No	24 (4.2)	0.441 (0.057-3.384)
Length of drug use
< 5 yr	176 (10.8)	1.0
≥ 5 yr	171 (6.4)	0.568 (0.262-1.233)
Frequency of drug use
< 75 times per month	217 (7.4)	1.0
≥ 75 times per month	130 (10.8)	1.516 (0.714-3.219)

OR: Odds ratio; CI: Confidence Interval; HCV: Hepatitis C virus; HIVAb: HIV-1 antibody; HBsAg: Hepatitis B surface antigen; HBsAb: Antibody to hepatitis B surface antigen.