Refined mapping of loss of heterozygosity on 1q31.1-32.1 in sporadic colorectal carcinoma

Table 3 The relationship between clinicopathological features and LOH of the loci on 1q31.1-32.1

		D1S2877		D1S412		D1S2757		D1S413		D1S2622		D1S2683		D1S2668
		T1	N2	T	N	T	N	T	N	T	N	T	N	T	N
Gender	Male	4	13	3	27	10	18	7	14	11	15	5	20	2	5
	Female	3	16	8	29	8	25	6	13	7	16	5	21	2	15
Age(yr)	> 60	5	24	9	39	13	32	10	18	16	22	10	29	2	16
	≤ 60	2	5	2	17	5	11	3	9	2	9	0	12	2	4
Location	Proximal colon	2	10	6	22	5	18	6	10	9	13	6	13	0	9
	Distal colon	2	8	4	15	5	11	3	7	5	8	0	14	1	7
	Rectum	3	11	1	19	8	14	4	10	4	10	4	14	3	4
Gross pattern	Massive	2	15	5	25	7	22	5	14	6	16	3	22	1	9
	Ulcerative	4	13	5	23	9	18	5	9	9	14	6	17	1	7
	Encroaching	1	1	1	8	2	3	3	4	3	1	1	2	2	4
Size (cm)	≥ 5	4	12	7	22	6	18	6	11	8	15	5	17	2	9
	< 5	3	17	4	34	12	25	7	16	10	16	5	24	2	11
LN metastasis	(+)	4	20	6	39	12	29	6	16	15	20	5	26	1	16
	(-)	3	9	5	17	6	14	7	11	3	11	5	15	3	4
Differentiation	Well	3	4	1	14	5	7	3	7	4	5	1	10	3	5
	Moderately	2	21	8	26	8	27	6	12	10	18	5	25	0	12
	Poorly	1	1	2	2	2	2	1	2	1	2	2	1	0	1
	Mucinous	1	3	0	14	3	7	3	6	3	6	2	5	1	2
Dukes stage	A	2	5	2	3	3	3	2	3	1	3	2	5	0	1
	B	1	4	3	14	3	11	5	8	2	8	3	10	3	3
	C	3	16	4	29	11	19	4	12	10	17	3	19	0	13
	D	1	4	2	10	1	10	2	4	5	3	2	7	1	3

T: Tumor; N: Normal.