Polymorphism of -765G > C COX-2 is a risk factor for gastric adenocarcinoma and peptic ulcer disease in addition to H pylori infection: A study from northern India

doi:10.3748/wjg.14.1498

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 14, Issue 10

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (2846)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-1) series, Tables (1-5) series.

Item

Count

PDF

383

HTML

2202

Figures (1-1)

141

Tables (1-5)

120

Sum=2846

Mar 14, 2008 (publication date) through May 10, 2024

Times Cited of This Article

Times Cited (25)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

H Pylori

World J Gastroenterol. Mar 14, 2008; 14(10): 1498-1503
Published online Mar 14, 2008. doi: 10.3748/wjg.14.1498

Table 2 Allelic distribution of COX-2 polymorphism in gastric adenocarcinoma, peptic ulcer disease and non-ulcer dyspepsia

COX-2 genotype	Gastric adenocarcinoma	Peptic ulcer disease	Non-ulcer dyspepsia
COX-2 genotype	(n = 62)	(n = 45)	(n = 241)
GG (%)	14 (22.6)	31 (68.9)	171 (71)
GC (%)	29 (46.8)	12 (26.7)	62 (25.7)
CC (%)	19 (30.6)	2 (4.4)	8 (3.3)
C carrier (%)¹	48 (77.4)	14 (31.1)	70 (29)

¹Gastric adenocarcinoma vs non-ulcer dyspepsia: P < 0.001; Gastric adeno-carcinoma vs peptic ulcer disease: P < 0.001; Peptic ulcer disease vs non-ulcer dyspepsia: P = 0.74.

Citation: Saxena A, Prasad KN, Ghoshal UC, Bhagat MR, Krishnani N, Husain N. Polymorphism of -765G > C COX-2 is a risk factor for gastric adenocarcinoma and peptic ulcer disease in addition to H pylori infection: A study from northern India. World J Gastroenterol 2008; 14(10): 1498-1503
URL: https://www.wjgnet.com/1007-9327/full/v14/i10/1498.htm
DOI: https://dx.doi.org/10.3748/wjg.14.1498