(-)-Epigallocatechin-3-gallate inhibits growth of gastric cancer by reducing VEGF production and angiogenesis

Figure 4 Decreased VEGF secretion (A) and inhibition of of VEGF mRNA expression (B) in tumor cells. SGC-7901 cells were treated with various concentrations of EGCG for 24 h and VEGF protein level in the supernatant was measured by ELISA and mRNA expression in tumor cells was examined by RT-PCR. Data are presented as mean ± SE (n = 3, ^aP < 0.05, ^bP < 0.01).