Metastatic suppressor genes inactivated by aberrant methylation in gastric cancer

Figure 3 Methylation-specific PCR (MSP) of gene PTPRG. M: Marker; u: Unmethylated (158 bp); m: Methylated (150 bp). A positive band was observed at 158 bp of non-methylation PCR of primary tumor, with a positive rate of 77.78% (28/36), while that of metastatic lymph nodes was 63.89% (23/36). A positive strap was observed at 150 bp of methylation PCR of metastatic lymph nodes, with a positive rate of 52.78% (19/36), while that of primary tumor was 25.0% (9/36) (P < 0.05).