Rapid Communication
Copyright ©2007 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 21, 2007; 13(43): 5760-5764
Published online Nov 21, 2007. doi: 10.3748/wjg.v13.i43.5760
Table 3 Combined effect of alcohol consumption and ADH2 and ALDH2 polymorphisms on esophageal cancer n (%)
ADH2Alcohol drinking status
Non-drinkers2
Current alcohol drinkers
Cases (n = 80)Controls (n = 128)OR (95% CI)1Cases (n = 111)Controls (n = 70)OR (95% CI)1
*2/*237 (46.3)65 (50.8)1.00 (References)41 (36.9)35 (50.0)1.88 (0.86-4.15)
*1/*2 or *1/*143 (53.7)63 (49.2)1.21 (0.63-2.33)70 (63.1)35 (50.0)3.94 (1.76-8.81)
ALDH2
*1/*133 (41.3)67 (52.3)1.00 (References)57 (51.4)41 (58.6)3.15 (1.39-7.13)
*1/*2 or *2/*247 (58.7)61 (47.7)2.03 (1.03-3.99)54 (48.6)29 (41.4)4.82 (2.06-11.27)
ADH2 and ALDH2
*2/*2*1/*115 (18.8)42 (32.8)1.00 (References)17 (15.3)20 (28.6)2.54 (0.84-7.67)
*1/*2 or *1/*1*1/*2 or *2/*225 (31.3)38 (29.7)2.46 (0.98-6.14)30 (27.0)14 (20.0)9.86 (3.10-31.38)