Influence of a nucleotide oligomerization domain 1 (NOD1) polymorphism and NOD2 mutant alleles on Crohn's disease phenotype

Table 2 Genotype at NOD2 polymorphisms in CD cases and healthy controls

Mutation	Group	Genotype count, n (%)			OR (95% CI)1	P2
		WT/WT	Heterozygous	Homozygous
R702W	CD	75 (77.32)	21 (21.65)	1 (1.03)	7.04 (1.58-31.30)	0.004
	Controls	48 (96.00)	2 (4.00)	0
G908R	CD	92 (94.85)	5 (5.15)	0		0.166
	Controls	50 (100)	0	0
L1007finsC	CD	89 (91.75)	8 (8.25)	0	4.40 (0.53-36.25)	0.167
	Controls	49 (98.00)	1 (2.00)	0

¹ORs and probability values for disease status associated with carriage of at least 1 mutant allele (heterozygous, compound heterozygous and homozygous were grouped together). ²P-values were calculated with the Fisher's Exact test when comparing controls and CD patients.