Risk factors for lymph node metastasis and evaluation of reasonable surgery for early gastric cancer

Table 2 Comparison of clinicopathological features between patients with and without lymph node metastasis

Factors	Node negative	Node positive	P value
Dissected nodes (mean ± SD)	19.3 ± 7.5	20.8 ± 6.9	0.188
Age, yr (mean ± SD)	53.9 ± 12.1	52.9 ± 13.2	0.606
Tumor maximum diameter (cm, mean ± SD)	3.1 ± 1.8	3.5 ± 1.8	0.197
Gender
Male	209	33
Female	66	14	0.465
Tumor location
Upper	11	0
Middle	53	9
Lower	207	38	0.435
Total	4	0
Depth of invasion
Mucosa	143	9
Submucosa	132	38	< 0.001
Histological type
Differentiated	130	12
Undifferentiated	145	35	0.007
Macroscopic type
Protruded	18	3
Flat	34	4	0.746
Depressed	223	40
Growth manner
Mass	87	15
Nest	79	12	0.891
Diffuse	109	20
lymphatic invasion
Negative	267	36
Positive	8	11	< 0.001

Differentiated: Papillary and tubular adenocarcinoma; Undifferentiated: Poorly differentiated adenocarcinoma and signet-ring cell carcinoma; Protruded:IandIIa; flat: IIb; depressed:IIc and III.