Impaired contractility and remodeling of the upper gastrointestinal tract in diabetes mellitus type-1

Figure 5 The distension-induced change in circumferential, longitudinal and radial stretch ratios are illustrated as function of the esophageal radius. The curves were obtained during smooth muscle relaxation with butylscopolamine. The data points represent the multiple measuring points during each distension of the patients and controls. Exponential trend lines (solid lines) of the patients and controls are shown. The shortening during distension was clearly reduced in the diabetic patients while the radial stretch was decreased.