Matrix metalloproteinase-9-1562C>T polymorphism may increase the risk of lymphatic metastasis of colorectal cancer

Table 3 Relationship of the C-1562T and R279Q genotypes with clinicopathological features of CRC patients

Parameters	C-1562T		R279Q
	CC	CT+TT	QQ	RQ+RR
Age (yr)
< 60 (n = 60)	49	11	1	59
≥ 60 (n = 77)	55	22	11	66c
Sex
Male (n= 70)	57	13	6	64
Female (n = 67)	47	20	6	61
Lymph node metastasis
N(-)(n = 87)	71	16	8	79
N(+)(n = 46)	29	17a	4	42
TNM classification
StageI(n = 26)	21	5	3	23
≥ Stage II(n = 107)	79	28	9	98
External membrane invasion
(+) (n = 102)	76	26	9	93
(-) (n = 31)	24	7	3	28

^aP = 0.022 vs CC genotype;

^cP = 0.012 vs QQ genotype, Fisher’s exact test.