Prognostic value of 13C-phenylalanine breath test on predicting survival in patients with chronic liver failure

Table 2 Variables with an independent prognostic value, as indicated by two Cox's models in patients with chronic liver failure (n = 118)

Variables	Coefficient	Hazard ratio1	SE	95% CI	Pvalue
1
Albumin (g/L)	-1.254	0.285	0.085	0.158-0.512	0.000
Total bilirubin (mmol/L)	0.149	1.161	0.051	1.065-1.265	0.001
Creatinine (mmol/L)	0.510	1.666	0.263	1.222-2.270	0.001
Age
≤ 60 yr	1.0002
> 60 yr	0.765	2.150	0.779	1.056-4.377	0.035
13C cumulative dose
< 5.0%	1.0002
≥ 5.0%	-0.798	0.449	0.178	0.206-0.979	0.044
2
Child Pugh class
A	1.0002
B	1.629	5.099	2.382	2.040-12.743	0.000
C	2.078	7.993	4.627	2.570-24.859	0.000
Creatinine (mmol/L)	0.417	1.518	0.200	1.173-1.966	0.002
Age,
≤ 60 yr	1.0002
> 60 yr	1.029	2.799	1.044	1.347-5.816	0.006
13C cumulative dose
< 5.0%	1.0002
≥ 5.0%	-1.081	0.338	0.140	0.150-0.762	0.009

¹Hazard ratio of Cox's proportional hazard regression;

²Reference category.