Comparison of four proton pump inhibitors for the short-term treatment of esophagitis in elderly patients

Table 2 Healing rates, drop-out patients, and side effects in elderly patients divided according to the different PPI regimens

		Per protocol analysis		Intention to treat analysis
Regimen	No. of patients	Cure rates %(N° of patients)	95% CI	Cure rates %(N° of patients)	95% CI	Drop outs	Side effects
Omeprazole	80	81.0	72.0–89.9	75.0	65.0–84.0	6 (7.5)	1
		60/74		60/80
Lansoprazole	80	90.7	84.1–97.2	85.0	77.0-92.8	5 (6.3)	1
		68/75		68/80
Pantoprazole	80	93.51	87.9–99.0	90.01	83.4-96.5	3 (3.8)	1
		72/77		72/80
Rabeprazole	80	94.62	89.4–99.7	88.82	81.5-95.6	5 (6.3)	1
		71/75		71/80
Total	320	90.0	86.6-93.4	84.7	80.7-88.6	19 (5.9)	4
		271/301		271/320			(1.4)

¹Pantoprazole vs Omeprazole: PP analysis: P = 0.039, ITT analysis P = 0.022;

²Rabeprazole vs Omeprazole: PP analysis: P = 0.022, ITT analysis P = 0.040.