H pylori seropositivity and cytokine gene polymorphisms

Table 5 Age, gender-adjusted ORs for H pylori seropositivity according to the combination of the two promoter genotypes of TNF and IL1B

	n	Hp (+)%1	Adjusted OR (95%CI)	P-value
TNF-1031/-857
TT/CC2	169	58.6	1.07 (0.70-1.64)	0.743
TC/CC2	104	63.5	1.38 (0.85-2.25)	0.195
CC/CC2	12	41.7	0.44 (0.13-1.57)	0.207
TT/CT2	84	59.5	1.06 (0.63-1.78)	0.830
TC/CT2	27	51.9	0.89 (0.39-2.02)	0.781
TT/TT2	14	21.4	0.15 (0.04-0.60)	0.007
IL1B-511/-313
CC/TT2	141	61.7	1.29 (0.83-2.01)	0.259
CT/CT2	191	54.5	0.74 (0.48-1.13)	0.159
TT/CC2	59	52.5	0.77 (0.43-1.39)	0.384

¹H pylori seropositivity (%).

²Each reference group represented all the other combinations of genotypes.

³ORs of the groups with < 7 subjects were not analyzed: CT/TT = 4, TT/TT = 4, CC/CT = 6, TT/CC = 2, and CT/CC = 3.