RhoA and RhoC -siRNA inhibit the proliferation and invasiveness activity of human gastric carcinoma by Rho/PI3K/Akt pathway

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Jul 7, 2007 (publication date) through Sep 20, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2007; 13(25): 3517-3522
Published online Jul 7, 2007. doi: 10.3748/wjg.v13.i25.3517

Table 2 The apoptosis rate of 5 groups with FACS (%) (mean ± SEM)

Group	Apoptosis rate (%)	P
1 RhoA,C-siRNA	19.07 ± 1.78	Compared with any group (P < 0.01 or P < 0.05)
2 RhoA-siRNA	7.13 ± 0.21	Compared with 4 or 5 group (P < 0.05), compared with 3 group (P > 0.05)
3 RhoC-siRNA	8.11 ± 0.17	Compared with 4 or 5 group (P < 0.05)
4 siRNA	1.23 ± 0.11	Compared with any group (P < 0.01 or P < 0.05)
5 LY294002	9.44 ± 1.28	Compared with 4 group (P < 0.01)

Citation: Sun HW, Tong SL, He J, Wang Q, Zou L, Ma SJ, Tan HY, Luo JF, Wu HX. RhoA and RhoC -siRNA inhibit the proliferation and invasiveness activity of human gastric carcinoma by Rho/PI3K/Akt pathway. World J Gastroenterol 2007; 13(25): 3517-3522
URL: https://www.wjgnet.com/1007-9327/full/v13/i25/3517.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i25.3517