COX-2 expression in gastric cancer and its relationship with angiogenesis using tissue microarray

Table 1 Expression of COX-2 protein in the gastric cancer and normal mucosa

Variable	n	COX-2 expression		COX-2-positive rate (%)	χ2	P
		-	+ - +++
Tissue character					12.191	0.000
Normal mucosa	37	15	22	59.46
Gastric cancer	87	11	76	87.36
Histologic type					5.391	0.495
Papillary adenocarcinoma	2	0	2	100.00
Well-differentiated adenocarcinoma	8	2	6	75.00
Moderately-differentiated adenocarcinoma	28	4	24	85.71
Poorly-differentiated adenocarcinoma	29	2	27	91.10
Mucin adenocarcinoma	12	0	12	100.00
Signet-ring cell carcinoma	5	1	4	80.00
Undifferentiated carcinoma	2	1	1	50.00
Metastasis					5.502	0.019
Negative	21	6	15	71.43
Positive	66	5	61	92.42
Depth of invasion					6.315	0.043
Muscle invasion	3	0	3	10.00
Subserosa invasion	68	20	48	70.59
Serosa exposure invasion	23	2	21	91.30
Borrman type					2.228	0.328
Borrman II	7	0	7	100.00
Borrman III	85	9	76	89.41
Borrman IV	4	1	3	75.00