Liver expression of steroid hormones and Apolipoprotein D receptors in hepatocellular carcinoma

Table 3 Relationship between PgR and Apo D Immunostaining values and clinico-pathological characteristics

	Progesterone receptors (PgR)		Apolipoprotein-D (Apo D)
Characteristics	n (%)	Score(median-range)	n (%)	Score(median-range)
Males	22 (84.6)	13.7 (0-61)	10 (28.5)	0 (0-81.1)
Age < 65 yr	17 (81)	9.7 (0-61)	7 (33.3)	0 (0-69.5)
Cirrhosis	24 (82.8)	14 (0-61)	11 (37.9)	0 (0-81.1)
HCV (+)	15 (93.8)	15.9 (3-61)	8 (50)	11 (0-81.11)
Alcohol etiology	11 (84.6)	9.7 (0-25)	5 (38.5%)	0 (0-80.4)
Uninodular	20 (80)	13.7 (0-61)	11 (44)	0 (0-81.1)
Size < median	17 (81)	13.7 (0-61)	6 (28.6)	0 (0-80.4)
Alfa-fetoprotein ≥
20 (ng/mL)	11 (91.7)	14 (5.7-61)	3 (25)	0 (0-80.4)
Histopathology
HCC-T	23 (82.1)	13.7 (0-61)	11 (39.3)	0 (0-81.1)
Death rate	13 (72.2)	11.75 (0-61)	8 (44.4)	0 (0-81.1)
Androgen receptors
Negative	5 (50)c	9.6 (0-20)a	4 (40)	0 (0-80.4)
Positive	21 (100)	14.2 (4-61)	8 (38.1)	0 (0-81.1)
Estrogen receptors
Negative	11 (73.3)	8 (0-34)a	6 (40)	0 (0-81.1)
Positive	15 (93.8)	17.2 (3-61)	6 (37.5)	0 (0-80.4)
Pg receptors
Negative	-	-	2 (40)	0 (0-24.4)
Positive			10 (38.5)	0 (0-81.1)
ApoD
Negative	16 (84.2)	13.7 (0-61)	-	-
Positive	10 (83.3)	13.8 (3-34)

^aP < 0.05,

^cP < 0.005. HCC-T: HCC trabecular.