Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity

Table 2 Correlation of NDRG1 expression with clinicopathologic variables in U.S. (Caucasian and African American) cases

	All U.S. cases (n = 77)				Caucasian (n = 43)				African American (n = 34)
	NDRG1				NDRG1				NDRG1
	Total (%)	+	-	P value	Total (%)	+	-	P value	Total (%)	+	-	P value
Age (yr)				0.079				0.092				0.464
> 66	45 (58.4)	19	26		26 (60.5)	10	16
< 66	32 (41.6)	20	12		17 (39.5)	11	6		19 (55.9)	9	10
Gender				0.074				0.255	15 (44.1)	9	6	0.153
Male	58 (75.3)	26	32		32 (74.4)	14	18
Female	19 (24.7)	13	6		11 (25.6)	7	4		26 (76.5)	12	14
Histopathological type				0.31				0.21	8 (23.5)	6	2	0.18
Well	47 (61.0)	20	27	0.15a	28 (65.1)	11	17	0.049a				0.88a
Moderate	23 (29.9)	14	9		14 (32.6)	10	4		19 (55.9)	9	10
Poor	2 (2.6)	1	1		0 (0)	0	0		9 (26.5)	4	5
Mucinous	5 (6.5)	4	1		1 (2.3)	0	1		2 (5.9)	1	1
Dukes’ stage				0.056				0.0063	4 (11.8)	4	0	0.88
A	7 (9.1)	1	6		4 (9.3)	0	4
B	28 (36.4)	14	14		16 (37.2)	8	8		3 (8.8)	1	2
C	23 (29.9)	16	7		14 (32.6)	11	3		12 (35.3)	6	6
D	19 (24.6)	8	11		9 (20.9)	2	7		9 (26.5)	5	4
Liver metastasis				0.39				0.072	10 (29.4)	6	4	0.59
Negative	58 (75.3)	31	27		34 (79.1)	19	15
Positive	19 (24.7)	8	11		9 (20.9)	2	7		24 (70.6)	12	12
Lymph node metastasis				0.212				0.28	10 (29.4)	6	4	0.52
Negative	35 (45.5)	15	20		20 (46.5)	8	12		15 (44.1)	7	8
Positive	42 (54.5)	24	18		23 (53.5)	13	10		19 (55.9)	11	8

^aP< 0.05vsmoderate.