Immunogenicity of recombinant hepatitis B virus vaccine in patients with and without chronic hepatitis C virus infection: A case-control study

Table 2 Characteristics of hepatitis C patients according to vaccine response (mean ± SD)

Characteristics	Non-responder(n = 10)	Responder(n =28)	P
Age (yr)	41.5 ± 11.3	41.0 ± 10.2	0.897
Male/Female	8/2	22/6	1.000
BMI (kg/m2)	26.6 ± 6.0	24.2 ± 4.1	0.192
Smoking n (%)	9 (90.0)	16 (57.1)	0.118
Alcohol n (%)	2 (20.0)	4 (14.3)	0.644
Hx of iv drug use n (%)	2 (20.0)	7 (25.0)	1.000
ALT (IU/L)	177.1 ± 293.9	78.3 ± 165.3	0.199
Liver disease
HAI grade (0-18)1	5.4 ± 2.1	5.6 ± 1.9	0.773
HAI stage (0-6)1	2.3 ± 1.1	2.6 ± 1.6	0.669
HCV genotype n (%)	8	26
1a	6 (75.0)	14 (53.8)	0.422
Other than 1a	2 (25.0)	12 (46.2)

¹According to Knodell’s histological activity index (HAI) as modified by Ishak et al[25]. Non-responder (anti-HBs < 10 IU/L); Responder (anti-HBs > 10 IU/L). Hx:history. .