Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicenter study

Table 2 Study of the correlation between clinical features of CrD and detection of ASCA

Clinical features of CrD	Numberof patients	Number of patientspositive for ASCA (%)	P
Age at diagnosis			< 0.001
≤ 20 yr	47	34 (72)
> 20 yr	58	20 (34)
Disease activity			NS
Quiescent	29	10 (34)
Active	71	40 (56)
Disease location			NS
Small bowel	17	11 (65)
Colon	28	10 (36)
Small bowel and colon	49	25 (51)
Anal complications			< 0.001
Presence	31	22 (71)
Absence	63	22 (35)
Extra intestinal manifestations			NS
Presence (except pancreatitis)	45	19 (42)
Pancreatitis	14	6 (43)
Absence	45	23 (51)

NS: no statistically significant difference; CrD: Crohn’s disease; ASCA: anti Saccharomyces cerevisiae antibodies. The total number of patients is different in each clinical feature because patients with one or two unknown items were nevertheless included.