Significance of hepatitis B virus surface antigen, hepatitis C virus expression in hepatocellular carcinoma and pericarcinomatous tissues

Table 3 Knodell scoring

Periportal Bridging Necrosis	Intralobular degeneration and focal necrosis	Portal inflammation	Fibrosis
0: None	0: None	0: None	0: None
1: Mild	1: Mild	1: Mild	1: Fibrous
	(< 1/3 lobules)	(< 1/3 lobules)	portal expansion
3: Moderate	3: Moderate	3: Moderate	3: Bridging
(< 50% circumference)	(< 2/3 lobules)	(< 2/3 lobules)	fibrosis
4: Marked	4: Marked	4: Marked ,dense	4: Cirrhosis
	(> 2/3 lobules)	(> 2/3 lobules)
5: Moderate
+ bridging
6: Marked
+ bridging
10: Multiple
lobular necrosis

HAI score is the combined score of necrosis, inflammation, and fibrosis.