A clinicopathological analysis in unsuspected gallbladder carcinoma: A report of 23 cases

Table 1 Analysis of past history of 23 UGC cases

Indications	UGC	PDGC
Age (yr)	59.57 ± 11.49	56.21 ± 11.62
Sex	M: 5, F: 18	M: 14, F: 19
Signs and symptoms
Jaundice (n)	4	1
Stomachache (n)	20	24
Febrile (n)	1	1
Dyspepsia (n)	4	5
Body weight loss (n)	4	6
Abdominal mass (n)	0	3
Absence of symptoms (n)	1 (preoperative diagnosis is adenoma)	3
Multiple pregnancies (≥ 3 times) (n)	13	14
Family malignancy history (n)	1, his father suffered with gastric cancer	2, their fathers respectively have lung cancer and hepatoma
Past history
Gastritis (n)	4	3
Gastric ulcer (n)	3	2
Hepatitis B (n)	5	10
Contact with schistosome pestilent water (n)	9	8
Coexisted with cholecystolithiasis (n)	17	8a
Size of cholecystolithiasis (> 1 cm) (n)	7	5
Multiple (n)	17	6b
Complicated with choledoch carcinoma (n)	1	0
Biliary tract diseases found preoperatively
Polypoid lesion of gallbladder wall (n)	3	7
Multiple (n)	2	6
Size (> 1 cm) (n)	2	3
Gallbladder wall thickening (n)	12	9
Gallbladder enlargement (n)	5	6
Atrophy of gallbladder (n)	2	1
Cholestasis (n)	2	0
Congenital capsular dilation of bile duct (n)	0	1
Coexist with extra-biliary-tract diseases
Splenomegaly (n)	0	4
Kidney multiple cystis (n)	0	2
Hemangiomas of liver (n)	0	2
Heparadiposum (n)	1	5
Hepatic cirrhosis (n)	1	2
Esophageal hiatal hernia (n)	0	1
Lateral ventral hernia (n)	0	3

^aP < 0.01 (χ² = 13.53, vs UGC);

^bP < 0.01 (χ² = 17.39, vs UGC).