Role of cyclooxygenase-2 in the carcinogenesis of gastrointestinal tract cancers: A review and report of personal experience

Table 2 Incidences of inflammatory changes, Barrett’s esophagus, and adenocarcinoma in a rodent duodenoesophageal reflux model

Wk	Group	n	RT#	BCH$	Incidence (%) of
					Barrett's esophagus	Adeno- carcinom
10	Control	10	100c	100c	10	0
	Celecoxib	5	40	40	0	0
20	Control	10	100c	100c	40	0
	Celecoxib	5	40	40	20	0
30	Control	10	100c	100c	50	10
	Celecoxib	5	40	40	40	0
40	Control	19	100c	100c	89a	47b
	Celecoxib	8	38	38	25	0

RT#, Regenerative thickening; BCH$, Basal cell hyperplasia;

^aP < 0.005 and

^cP < 0.05, respectively, control vs celecoxib group, Fisher's exact test.