Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis

Figure 3 Recording of pancreatic microcirculatory blood flow in Group 3. Rats were injected with taurocholic acid and treated 30 min later with bupivacaine (0.4%, 20 µL) in the epidural catheter. Induction of AP caused a significant decrease in pancreatic microcirculatory blood flow. After induction of epidural anesthesia, mean pancreatic microcirculatory blood flow increased again significantly within 45 min, reaching approximately 50% of baseline values.