Down-expression of tumor protein p53-induced nuclear protein 1 in human gastric cancer

Table 2 Correlation between TP53INP1 expression levels and clinicopathologic features in gastric cancer

	TP53INP1-positive(n=91 of 142 patients)	TP53INP1-negative (n=51 of 142 patients)	P value
Age (years)
<60	31	18	NS
≥60	60	33
Sex
Male	68	36	NS
Female	23	15
Location
Cardia	20	22
Body	58	26	0.0193
Antrum	13	3
Histological type
Differentiateda	62	14
Undifferentiatedb	29	37	<0.0001
Tumor invasion
T1a+T1b	23	4	0.0111
T2+T3+T4	68	47
Lymph node metastasis
Positive	5	11	0.0037
Negative	86	40
Liver metastasis
Positive	0	5	0.0024
Negative	91	46
Lymphatic invasion
Positive	50	42	0.0010
Negative	41	9

NS: not significant.

^aDifferentiated type corresponds to well and moderately differentiated tubular and papillar tumors (intestinal type).

^bUndifferentiated type includes poorly differentiated and signet-ring cell carcinomas (diffuse type).