Treatment of hepatocellular carcinoma accompanied by portal vein tumor thrombus

Table 4 Hepatic resection for hepatocellular carcinoma with portal vein tumor thrombus

Lead author	Yr	Number ofpatients	Location oftumor thrombus	Treatment	Operative mortalityrate (%)	5-Year survivalrate (%)	Median survivaltime (mo)
Kumada K et al[54]	1990	13	Vp4	Hx.	-	-	-
Yamaoka Y et al[55]	1992	29	Vp3, 4	Hx.	11	(11.6:3YSR)	-
Ikai I et al[56]	1998	29	Vp4	Hx.	-	4	-
		29	Vp3	Hx.	-	11	-
Ohkubo T et al[57]	2000	47	Vp2, 3, 4	Hx.	0	23.9	14
Wu CC et al[58]	2000	15	Vp4	Hx.	0	26.4	-
		97	Vp1, 2, 3	Hx.	3.1	28.5	-
Minagawa M et al[59]	2001	18	Vp2, 3, 4	TACE → Hx.	0	42	31
Fukuda S et al[60]	2002	19	Vp3, 4,	Hx. → HAI etc.	0	36.3	22.1
			Vv2, 3, B3, 4
Poon RT et al[61]	2003	20	Vp3, 4,	Hx.	5.7	13.3	6
			Vv2
Lau WY et al[62]	2004	7	Vp4	PIAF→Hx. or Yttrium 90 ia + doxorubicin iv → Hx.	4.1	56	a
Pawlik TM et al[63]	2005	102	Vp3, Vv2, 3	Hx.	5.9	10	11
Ikai I et al[64]	2006	78	Vp3, Vp4	Hx.	3.8	10.9	8.9
Le Treut YP et al[65]	2006	26	Vp3, 4, Vv2, 3	Hx.	11.5	13	9
Zhou J et al[66]	2006	381	Vp2, 3, 4	Hx.	-	12	-

^aSurvival curves remain above a survival rate of 50%. PIAF: Doxorubicin, CDDP, 5-FU iv + Interferon-α sc; Hx.: Hepatic resection; HAI: Hepatic arterial infusion chemotherapy; Vv2: The main trunk of hepatic vein; Vv3: The inferior vena cava; B3: 1^st order branches of bile duct; B4: The common hepatic duct; YSR: Year survival rate.