Hepatotoxicity induced by cyproterone acetate: A report of three cases

Table 2 CPA-induced hepatotoxicity: review of 14 cases

Reference	Age (yr)	Liver injury	Doses (mg)	Latency (mo)	Duration1(wk)
Levesque[1]	78	ALF	200	6	2
Parys[11]	65	ALF	300	12	7
Parys[11]	83	ALF	300	15	2
Bressollette[16]	79	ALF	300	10	2
Hirsch[14]	92	ALF	100	4	5
Murphy[2]	73	ALF	100	4	Alive
Lombardi[15]	84	ALF			1
Friedmann[13]	81	ALF	300	6	7
Friedmann[13]	66	ALF	300	2	4
Giordano[10]	87	AH	300		Alive
Manolakopoulos[9]	76	AH	150	7	Alive
Savidou	82	AH	200	12	Alive
Savidou	83	AH	300	7	6
Savidou	78	AH	300	3	Alive
Mean	79.1		242.3	7.3	4
Median	80		300	6.5	4
SD	7.4		81.2	4	2.3

¹Duration between onset of jaundice and death; ALF: Acute liver failure; AH: Acute hepatitis.