Colon cancer and the immune system: The role of tumor invading T cells

doi:10.3748/wjg.v12.i45.7233

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Dec 7, 2006 (publication date) through Jun 16, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 7, 2006; 12(45): 7233-7238
Published online Dec 7, 2006. doi: 10.3748/wjg.v12.i45.7233

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Figure 2 The role of different T cell subsets in colorectal cancer. Activated CD4+ T cells can release growth factors and thereby lead to tumor progression or activate tumor specific CD8+ T cells. Secretion of TGFβ can induce adaptive Tregs, which may suppress the anti-tumor immune response. Once activated, Tregs can be suppressed by IL-6 derived from CD4+ T cells.

Citation: Waldner M, Schimanski CC, Neurath MF. Colon cancer and the immune system: The role of tumor invading T cells. World J Gastroenterol 2006; 12(45): 7233-7238
URL: https://www.wjgnet.com/1007-9327/full/v12/i45/7233.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i45.7233