Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study

Table 1 Characteristics of the 79 patients at the time of inclusion

Characteristics	Group 1(Hepatitis)	Group 2(Cirrhosis)	Group 3(Controls)
Patients (n)	41	12	26
Age (yr)	50 ± 13	60 ± 11a	49 ± 12
Gender (M/F)	14/27	5/7	13/13
Route of transmission, n (%)
Transfusion	10 (24%)	5 (42%)	-
IVDU	11 (27%)	3 (25%)	-
Other or unknow	20 (49%)	4 (33%)	-
Duration of infection (yr)	19 ± 9	23 ± 5	-
Alcohol intake (g/d)	12 ± 23	12 ± 14	-
AST (xULN)	1.5 ± 1.1	3.7 ± 2.4b	-
ALT (xULN)	1.7 ± 1.3	3.7 ± 2.8b	-
GGT (xULN)	1.4 ± 0.7	2.0 ± 1.9	-
HCV genotype, n (%)			-
1	24 (58%)	8 (67%)	-
2/3	11 (27%)	4 (33%)	-
Other	6 (15%)	0 (0%)	-
HCV viral load (IU/mL)	827 889 ± 123 741	923 026 ± 181 866	-
Histological lesions (Metavir)
Activity, n (%)
A0-1	16 (39%)	0 (0%)	-
A2-3	25 (61%)	12 (100%)a	-
Fibrosis, n (%)
F0-1	16 (39%)	-	-
F2	23 (56%)	-	-
F3	2 (5%)	-	-
F4	-	12 (100%)	-

IVDU: Intravenous drug use; ULN: Upper limit of normal value;

^aP < 0.05,

^bP < 0.01 vs hepatitis group.