Hepatitis B genotypes: Relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia

Table 3 Hepatitis B virus genotype D patients’ biochemical, hematological and virological parameters distributed across the four groups (mean ± SD)

Parameter	Group 1(n = 10)	Group 2(n = 21)	Group 3(n = 16)	Group 4(n = 10)	P
Age (yr)	45 ± 18	35 ± 9.9	52.1 ± 7.7	61 ± 12	0.015
ALT (U/L)	40.3 ± 8	176.9 ± 100.7	54.1 ± 30.4	99.3 ± 79.9	0.001
AST (U/L)	21.1 ± 6.5	78.6 ± 56.8	63.8 ± 48.5	158.3 ± 167.6	0.001
ALP (U/L)	98.6 ± 39.9	112.6 ± 41	143.8 ± 6.2	239.9 ± 201	0.001
Bilirubin (μmol/L)	10.6 ± 4.9	14.1 ± 10.2	48.6 ± 60.4	27.8 ± 23.2	0.001
Albumin (g/L)	41.5 ± 3.2	37.8 ± 4.6	27.8 ± 7.9	24.7 ± 8.4	0.007
WBC (109/L)	7.5 ± 2.2	6.3 ± 1.7	6.12 ± 3.1	6.2 ± 1.9	0.100
Hemoglobin (g/L)	127.7 ± 42.5	129.2 ± 57.5	65.5 ± 55.9	62.5 ± 54.5	0.704
Platelets (109/ L)	250 ± 84.3	207.2 ± 56	130.8 ± 56	217.6 ± 97.4	0.113
HBeAg -/+	5/5	12/9	15/1	9/1	0.024

ALT: Alanine transaminase; AST: Aspartate transaminase; ALP: Alkaline phosphatase; GGT: Gamma glutamyl transpeptidase; WBC: White blood cells.