Precore/basal core promoter mutants and hepatitis B viral DNA levels as predictors for liver deaths and hepatocellular carcinoma

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Nov 7, 2006 (publication date) through Apr 30, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Liver Cancer

World J Gastroenterol. Nov 7, 2006; 12(41): 6620-6626
Published online Nov 7, 2006. doi: 10.3748/wjg.v12.i41.6620

Table 6 Univariate analysis of factors associated with development of HCC

Factor	HCC	No HCC	P
n	31	369
Age (yr) (mean ± SD)	57.4 ± 2.7	46.9 ± 0.8	0.0002
Male/Female	28/3	254/115	0.006
Asian/Non-Asian	26/5	288/81	0.4
Cirrhosis			< 0.0001
Yes	22/139	117/139
No	9/261	252/261
BCP 1762/1764 mutant			0.007
Yes	18	106
No	6	148
PC 1896 mutant			0.05
Yes	14	98
No	17	253
Genotype			0.2
A	2	54
B	8	84
C	19	147
HBeAg			0.3
+	12	165
-	18	180
Baseline HBV-DNA level (mean ± SD, copies/mL)	6.3 ± 1.4 Log₁₀	6.1 ± 2.3 Log₁₀	0.6

Citation: Tong MJ, Blatt LM, Kao JH, Cheng JT, Corey WG. Precore/basal core promoter mutants and hepatitis B viral DNA levels as predictors for liver deaths and hepatocellular carcinoma. World J Gastroenterol 2006; 12(41): 6620-6626
URL: https://www.wjgnet.com/1007-9327/full/v12/i41/6620.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i41.6620