Strong prognostic value of nodal and bone marrow micro-involvement in patients with pancreatic ductal carcinoma receiving no adjuvant chemotherapy

Table 1 Characteristics of patients and tumors

Variable	n	Ber-EP4 positive cellsin lymph nodes (n)
All patients	106	73
Male	59	42
Female	47	31
Primary Tumor
Carcinoma in situ	1	0
pT1	6	3
pT2	36	26
pT3	59	40
pT4	4	4
Nodal status
Negative (pN0)	51	29*
Positive (pN1)	55	44*
Tumor Grade
Well differentiated (G1)	5	4
Moderately differentiated (G2)	54	35
Poorly differentiated (G3)	47	34
Resection margin
Negative (R0)	90	59
Positive (R1)	16	14
Tumor cells in Bone marrow
Yes	14	9
No	45	31
Not analysed	47	33

Nodal status was detected both histopathologically and immunohisto-chemically. Bone marrow micrometastases were detected by immunohisto-chemistry. P = 0.035.