Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice

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Oct 28, 2006 (publication date) through Jun 16, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 28, 2006; 12(40): 6464-6472
Published online Oct 28, 2006. doi: 10.3748/wjg.v12.i40.6464

Table 1 Microscopic assessment of histologic changes in DSS colitis

A: Grade of crypt lesion	Score
Intact crypt	0
Grade 1: Loss of the basal third	1
Grade 2: Loss of two thirds	2
Grade 3: Loss of entire crypt	3
Grade 4: Erosion	4
B: Extension of each grade of crypt lesion as % of total mucosal surface	0-100
Crypt lesion score	Σ (A × B)
Grade of inflammation, epithelial regeneration or crypt distortion	Score
Absent	0
Mild	1
Moderate	2
Severe	3

Crypt lesion, acute and chronic inflammation, epithelial regeneration and crypt distortion are scored separately.

Citation: Santana A, Medina C, Paz-Cabrera MC, Díaz-Gonzalez F, Farré E, Salas A, Radomski MW, Quintero E. Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice. World J Gastroenterol 2006; 12(40): 6464-6472
URL: https://www.wjgnet.com/1007-9327/full/v12/i40/6464.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i40.6464