Cytotoxic T-lymphocyte antigen 4 gene polymorphisms and susceptibility to chronic hepatitis B

Table 2 Relation between frequencies of genotypes of CTLA-4 +49, -318, -1172 CTLA-4 polymorphisms and mean AST and ALT levels in subjects with chronic hepatitis, chronic hepatitis on first course of treatment, inactive carrier, non-responders to first course of treatment

	TC 1172 genotype	Mean	SE
AST	1172 T+C–	35.1944	3.7008
	1172 T+C+	25.3077	2.3325
	1172 T–C+	35.0000	14.0000
	TC 318 genotype	Mean	SE
AST	318 T+C+	29.1000	5.8299
	318 T–C+	33.5366	3.1455
There are no valid cases for AST. Statistics cannot be computed.
	AG 49 genotype	Mean	SE
AST	49 G+A–	32.6667	6.5362
	49 G+A+	32.3750	3.9811
	49 G–A+	32.8462	4.3960
	TC 1172 genotype	Mean	SE
ALT	1172 T+C–	40.9167	5.0528
	1172 T+C+	28.9231	4.3742
	1172 T–C+	50.0000	20.0000
	TC 318 genotype	Mean	SE
ALT	318 T+C+	33.5000	7.0683
	318 T–C+	39.3659	4.4751
There are no valid cases for ALT. Statistics cannot be computed.
	AG 49 genotype	Mean	SE
ALT	49 G+A–	43.1111	9.3592
	49 G+A+	40.1875	5.7018
	49 G–A+	35.3077	5.9497