Expression and prognostic role of molecular markers in 99 KIT-positive gastric stromal tumors in Taiwanese

Table 4 Univariate and multivariate analyses for overall survival rates of individual parameters of GIST patients

	Univariate			Multivariate
	Risk	95%CI	P	Risk	95%CI	P
Age ≥60/<60 yr	0.90	0.39–2.06	0.81	–	–	–
Gender M/F	2.68	1.16–6.20	0.021a	–	–	0.097
Tumor size ≥5/<5 cm	19.01	2.56–141.1	0.004a	10.17	1.34–76.9	0.001a
Mitoses ≥5/<5/50 HPF	10.30	3.48–30.4	<0.001a	5.22	1.70–15.9	0.001a
Tumor location fundic-cardiac/body-antrum	1.07	0.58–1.96	0.81	–	–	–
Hemoglobin ≥100/<100	1.98	0.78–5.05	0.14	–	–	–
Cell type spindle/non-spindle	1.29	0.76–2.18	0.34	–	–	–
Cellularity low+intermediate/high	1.21	0.64–2.17	0.35	–	–	–
Pleomorphism +/-	0.90	0.39–2.09	0.82	–	–	–
P53 +/-	11.29	2.64–48.2	0.001a	4.84	1.08–21.6	0.012a
Ki67 +/-	2.30	1.01–5.26	0.048a	–	–	0.70
PCNA above or below median	2.75	1.13–6.70	0.025a	–	–	0.74
CD 34 +/-	1.98	0.58–6.70	0.27	–	–	–
SMA +/-	1.38	0.54–3.52	0.48	–	–	–
Desmin +/-	0.76	0.18–3.27	0.72	–	–	–
S-100 +/-	2.28	0.67–7.70	0.18	–	–	–