Expression and prognostic role of molecular markers in 99 KIT-positive gastric stromal tumors in Taiwanese

Table 3 Univariate and multivariate analyses for disease free survival rates of individual parameters of GIST patients

	Univariate			Multivariate
	Risk	95%CI	P	Risk	95%CI	P
Age ≥60/<60 yr	1.01	0.45–2.25	0.98	–	–	–
Gender M/F	2.38	1.05–5.36	0.036a	–	–	0.1
Tumor size ≥5/<5 cm	6.16	1.83–20.6	0.003a	3.43	1.12–11.8	0.025a
Mitoses ≥5/<5/50 HPF	6.30	2.49–15.9	<0.001a	3.28	1.25–8.59	0.009a
Tumor location fundic-cardiac/body-antrum	0.99	0.54–1.81	0.98	–	–	–
Hemoglobin ≥100/<100	2.21	0.86–5.63	0.095	–	–	–
Cell type spindle/non-spindle	1.23	0.73–2.08	0.42	–	–	–
Cellularity low+intermediate/high	1.26	0.82–2.16	0.38	–	–	–
Pleomorphism +/-	0.82	0.36–1.89	0.65	–	–	–
P53 +/-	12.1	2.83–51.3	0.001a	6.45	1.45–28.7	0.002a
Ki67 +/-	2.52	1.12–5.68	0.026a	–	–	0.41
PCNA above or below median	2.97	1.23–7.17	0.015a	–	–	0.42
CD 34 +/-	3.07	0.41–22.7	0.27	–	–	–
SMA +/-	1.34	0.53–3.37	0.54	–	–	–
Desmin +/-	0.74	0.17–3.16	0.68	–	–	–
S-100 +/-	2.19	0.65–1.37	0.20	–	–	–

^aP<0.05 vs others.