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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 7, 2006; 12(37): 5941-5950
Published online Oct 7, 2006. doi: 10.3748/wjg.v12.i37.5941
Published online Oct 7, 2006. doi: 10.3748/wjg.v12.i37.5941
Author | Design | Group (Dose/d) (n) | Results | |
Probiotic | Comparator | |||
Induction of remission of ulcerative colitis | ||||
Kanauchi 2003 [112] | Open label | Conventional therapy + Germinated barley foodstuff (20-30 g) (21) | Conventional therapy | Improved UCDAI |
Furrie 2005 [114] | DB, R, C | B. longum (2 × 1011) + inulin/oligofructose (6 g) (9) | Placebo (9) | Sigmoidoscopy scores reduced (P = 0.06) β-defensins, TNFα , IL-1α levels decreased (P < 0.05) |
Maintenance of remission of ulcerative colitis | ||||
Hanai 2004 [113] | Open label | Conventional therapy + Germinated barley foodstuff (20 g) (22) | Conventional therapy (37) | Improved UCDAI and endoscopic scores |
Induction of remission of Crohn’s disease | ||||
Lindsay 2006 [115] | Open label | Fructo-oligosaccharides (15 g) (10) | None | Increase in IL-10 expressing intestinal dendritic cells |
- Citation: Ewaschuk JB, Dieleman LA. Probiotics and prebiotics in chronic inflammatory bowel diseases. World J Gastroenterol 2006; 12(37): 5941-5950
- URL: https://www.wjgnet.com/1007-9327/full/v12/i37/5941.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i37.5941