-765G > C COX-2 polymorphism may be a susceptibility marker for gastric adenocarcinoma in patients with atrophy or intestinal metaplasia

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Sep 14, 2006 (publication date) through May 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Gastric Cancer

World J Gastroenterol. Sep 14, 2006; 12(34): 5473-5478
Published online Sep 14, 2006. doi: 10.3748/wjg.v12.i34.5473

Table 2 Genotype distribution of COX-2 -765G > C polymorphism

Genotype	Controls(n = 210)		Atrophy or intestinalmetaplasia(n = 37)		Gastricadenocarcinoma(n = 73)
Genotype	n (%)	P¹	n (%)	P²	n (%)
GG	130 (62)	0.197	27 (73)	0.018	36 (49)
GC	67 (32)	0.357	9 (24)	0.046	32 (44)
CC	13 (6)	0.398	1 (3)	0.339	5 (7)
C carrier	80 (38)	0.197	10 (27)	0.018	37 (51)

¹vs Atrophy or intestinal metaplasia group (chi-square test); ²vs Gastric adenocarcinoma group (chi-square test).

Citation: Pereira C, Sousa H, Ferreira P, Fragoso M, Moreira-Dias L, Lopes C, Medeiros R, Dinis-Ribeiro M. -765G > C COX-2 polymorphism may be a susceptibility marker for gastric adenocarcinoma in patients with atrophy or intestinal metaplasia. World J Gastroenterol 2006; 12(34): 5473-5478
URL: https://www.wjgnet.com/1007-9327/full/v12/i34/5473.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i34.5473