Usefulness of duodenal biopsy during routine upper gastrointestinal endoscopy for diagnosis of celiac disease

Table 2 Clinical and immune-histological characteristics of celiac patients

Gender
Female	18 (81.8%)
Male	4 (18.2%)
Age (yr)	50 (19-77)
Clinical characteristics
Malabsorption syndrome	12 (54.5%)
Anemia	14 (63.6%)
Dermatitis herpetiformis	5 (22.7%)
Abnormal liver function test	7 (31.8%)
Celiac relatives	2 (9.1%)
Histology (Marsh type):
I	3 (13.6%)
II	1 (4.5%)
III	18 (81.8%)
Serology1
AGA	13 (86.7%)
EMA	17 (89.5%)
TTG	8 (88.9%)
HLA-DQ22	18 (100%)
Autoimmune associated diseases3	2 (9.1%)
Mortality4	2 (9.1%)

n (%) are shown for categorical variables, while the median (range) is shown for age.

¹Serological analysis was performed using antigliadin (AGA) in 15, anti-endomysium (EMA) in 19 and tissue-trans-glutaminase antibodies (TTG) in 9 patients;

²Genetic study was performed in 18 patients;

³Addison disease (1) and juvenile arthritis (1);

⁴Stroke (1) and non-Hodgkin lymphoma (1).