Slow transit constipation: A functional disorder becomes an enteric neuropathy

Figure 1 Interstitial cells of Cajal (arrows) at myenteric plexus level in a control subject (A) and in a patient with slow transit constipation (B). Note the considerable decrease of these cells in the patient (CD117, original magnification x 40). Panels C and D show the enteric glial cells (arrows) in the myenteric plexus of a control and of a patients with slow transit constipation, respectively. Note the important reduction of these cells in the patient, where only a few ones may be identified (S100, original magnification x 40).