Slow transit constipation: A functional disorder becomes an enteric neuropathy

Table 1 Rome II criteria for functional constipation (adapted from reference 4)

Two or more of the following for at least 12 wk (not necessarily consecutive) in the preceding 12 mo:
• Straining during > 25% of bowel movements;
• Lumpy/hard stools for > 25% of bowel movements;
• Sensation of incomplete evacuation for > 25% of bowel movements;
• Sensation of anorectal blockage for > 25% of bowel movements;
• Manual manoeuvres to facilitate > 25% of bowel movements (e.g., digital evacuation or support of the pelvic floor);
• < 3 bowel movements per week Loose stools are not present, and there are insufficient criteria for irritable bowel syndrome