Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells

Table 3 Effect of hot water-extracted LBE and RGE on cell proliferation in human hepatocellular carcinoma (HA22T/VGH) cells after 24 h incubation (n = 6, mean ± SD)

	Cell proliferation (% of control)
Control	100.0 ± 4.2dfh
2 g/L LBE	86.0 ± 5.9bch
5 g/L LBE	77.0 ± 5.1abh
10 g/L LBE	56.8 ± 3.9bdf
2 g/L RGE	86.3 ± 5.9bfh
5 g/L RGE	74.3 ± 7.5bd
10 g/L RGE	70.3 ± 7.7bd

^bP < 0.01 vs control;

^aP < 0.05,

^dP < 0.01 vs 2 g/L corresponding treatment;

^cP < 0.05,

^fP < 0.01 vs 5 g/L corresponding treatment;

^hP < 0.01 vs 10 g/L corresponding treatment.