Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats

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Jan 14, 2006 (publication date) through Apr 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2006; 12(2): 259-264
Published online Jan 14, 2006. doi: 10.3748/wjg.v12.i2.259

Table 3 MDA, CAT and GPx levels in liver tissues of different groups after treatment (mean ± SE)

Group	MDA(nmol/mg pr)	CAT(U/mg pr)	GPx(U/mg pr)
Control	7.00 ± 2.29	3.20 ± 0.83	0.72 ± 0.25
Caerulein	20.89 ± 10.13^a	1.09 ± 0.35^a	0.33 ± 0.09^g
	9.66 ± 3.65^c	3.69 ± 1.35^e	0.50 ± 0.12^c
Caerulein + antioxidant mixture	10.49 ± 3.03^c	3.12 ± 1.02^e	0.61 ± 0.26^c

^aP < 0.005 vs control; ^cP < 0.05 vs caerulein; ^eP < 0.005 vs caerulein, ^gP < 0.05 vs control.

Citation: Eşrefoğlu M, Gül M, Ateş B, Batçıoğlu K, Selimoğlu MA. Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats. World J Gastroenterol 2006; 12(2): 259-264
URL: https://www.wjgnet.com/1007-9327/full/v12/i2/259.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i2.259