Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats

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Jan 14, 2006 (publication date) through May 10, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2006; 12(2): 259-264
Published online Jan 14, 2006. doi: 10.3748/wjg.v12.i2.259

Table 2 MDA, CAT and after treatment GPx levels in pancreatic tissues of different groups after treatment (mean ± SE)

Groups	MDA(nmol/mg pr)	CAT(U/mg pr)	GPx(U/mg pr)
Control	1.74 ± 0.23	10.29 ± 0.68	0.59 ± 0.05
Caerulein	2.63 ± 0.22^a	2.78 ± 0.28^g	0.10 ± 0.00^g
Caerulein + melatonin	1.90 ± 0.17^c	15.63 ± 0.67^e	1.72 ± 0.29^e
Caerulein + antioxidant mixture	1.30 ± 0.15^e	7.02 ± 1.84	1.15 ± 0.18

^aP < 0.05 vs control; ^cP < 0.05 vs caerulein; ^eP < 0.005 vs caerulein; ^gP < 0.005 vs control.

Citation: Eşrefoğlu M, Gül M, Ateş B, Batçıoğlu K, Selimoğlu MA. Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats. World J Gastroenterol 2006; 12(2): 259-264
URL: https://www.wjgnet.com/1007-9327/full/v12/i2/259.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i2.259