Production of reactive oxygen species and expression of inducible nitric oxide synthase in rat isolated Kupffer cells stimulated by Leptospira interrogans and Borrelia burgdorferi

Figure 2 Effect of spirochete opsonization on the chemiluminescence (CL) signal. Each value represents the mean ± SD of three independent experiments carried out at a ratio of 500 spirochetes/KCs using unopsonized (white bars) and opsonized (grey bars) bacteria. Note that the ROS production induced by borreliae was about twice the ROS generation of leptospirae.