Association of smoking, alcohol drinking and dietary factors with esophageal cancer in high- and low-risk areas of Jiangsu Province, China

Table 4 OR¹ and 95% CI of alcohol drinking in EC of Dafeng and Ganyu

Alcohol drinking		Dafeng (high-risk)	Ganyu (low-risk)
Alcohol drinking
	Never	1.00 (Referent)	1.00 (Referent)
	Ever	1.01 (0.70-1.46)	1.71 (1.02-2.88)
	P value	0.964	0.043
Age of first drink2
	<20	0.83 (0.44-1.58)	2.59 (1.03-6.50)
	20-34	1.23 (0.79-1.91)	1.95 (1.08-3.53)
	≥35	0.81 (0.48-1.35)	1.18 (0.56-2.47)
	P value for trend	0.815	0.012
Duration of drinking (yr)2
	1-24	0.96 (0.56-1.59)	1.28 (0.58-2.79)
	25-34	0.89 (0.48-1.64)	1.48 (0.75-2.94)
	35-44	1.57 (0.92-2.70)	1.47 (0.71-3.01)
	≥45	0.77 (0.43-1.40)	1.88 (0.95-3.75)
P value for trend		0.834	0.061
Alcohol consumption 10 years ago2 (pure ethanol mL/wk)
	1-249	0.87 (0.49-1.54)	0.79 (0.36-1.74)
	250-499	1.06 (0.60-1.89)	0.61 (0.30-1.25)
	500-749	0.97 (0.52-1.79)	1.63 (0.77-3.43)
	≥750	1.10 (0.63-1.93)	1.27 (0.71-2.28)
	P value for trend	0.74	0.223

¹ Matched by age and gender, further adjusted for level of education, past economic status (group) and tobacco smoking;

² Never-drinkers were used as the reference group.