Association of smoking, alcohol drinking and dietary factors with esophageal cancer in high- and low-risk areas of Jiangsu Province, China

Table 1 Characteristics among EC cases and controls in Dafeng and Ganyu ¹n (%)

Characteristics		Dafeng (high-risk)		Ganyu (low-risk)		P value2
		Case (n=291)	Control (n=291)	Control (n=240)	Case (n=240)
Gender: Male		200 (68.7)	200 (68.7)	181 (75.4)	181 (75.4)	0.088
	Female	91 (31.3)	91 (31.3)	59 (24.6)	59 (24.6)
Age (yr) Mean±SD		64.8 ± 8.6	64.6 ± 8.9	65.4 ± 10.3	65.6 ± 10.4	0.002
	<50	14 (4.8)	17 (5.8 )	19 (7.9)	17 (7.1)
	50-59	61 (30.0)	59 (20.3)	48 (20.0)	51 (21.3)
	60-69	137(47.1)	137 (47.1)	78 (32.5)	76 (31.7)
	70-79	71 (24.4)	69 (23.7)	77 (32.1)	78 (32.5)
	≥80	8 (2.8)	9 (3.1)	18 (7.5)	18 (7.5)
Level of education
	Illiterate	156 (53.6)	130 (44.7)	138 (57.7)	164 (68.6)	<0.001
	Primary school	95 (32.7)	119 (40.9)	63 (26.4)	54 (22.6)
	Secondary school & above	40 (13.7)	42 (14.4)	38 (15.9)	21 (8.8 )
Past economic status(By separate cut-off points)
Median (CNY/yr)		1250	1500	1000	775	0.235
	1 (lowest)	97 (33.5)	55 (19.0)	38 (16.2)	47 (20.3)
	2	68 (23.5)	64 (22.1)	71 (30.2)	87 (37.5)
	3	73 (25.2)	96 (33.1)	71 (30.2)	59 (25.4)
	4 (highest)	52 (17.9)	75 (25.9)	55 (23.4)	39 (16.8)
Smoking status3
	Neversmoker	92 (31.6)	122 (41.9)	95 (39.6)	82 (34.2)	0.067
	Former-smoker	71 (24.4)	64 (22.0)	19 (7.9)	17 (7.1)
	Current smoker	128 (44.0)	105 (36.1)	126 (52.5)	141 (58.7)
Alcohol drinking status4
	Never drinker	175 (60.1)	181 (62.2)	143 (59.6)	131 (54.6)	0.076
	Former drinker	5 (1.7)	7 (2.4)	7 (2.9)	7 (2.9)
	Current drinker	111 (38.1)	103 (35.4)	90 (37.5)	102 (42.5)
Encountered misfortune in past10 yr:
	No	54 (18.6)	41 (14.2)	33 (14.0)	54 (23.3)	0.008
	Yes	237 (81.4)	248 (85.8)	203 (86.0)	178 (76.7)
History of family cancer
	No	112 (38.5)	86 (29.6)	16 (6.7)	29 (12.1)	<0.001
	Yes	179 (61.5)	205 (70.5)	224 (93.3)	211 (87.9)
Body mass index
	<18.5	60 (20.8)	27 (9.3)	18 (7.6)	31 (13.4)	0.014
	18.5-23.9	182 (63.0)	192 (66.2)	161 (67.9)	155 (67.1)
	23.9-27.9	34 (11.8)	60 (20.7 )	46 (19.4)	28 (12.1)
	≥28	13 (4.5)	11 (3.8)	12 (5.1)	17 (7.4)

¹ Some strata do not match the total because of missing values;

² The P-value for comparing the distribution of factors between the two counties;

³ Never-smokers and ever-smokers were used for comparing the smoking habits between the two counties;

⁴ Because of the few numbers of former drinkers in both two counties, alcohol drinking status was categorized to never-drinkers and ever-drinkers for the comparison between the two counties and following analyses.