Jumbo biopsy is useful for the diagnosis of colonic prolapsing mucosal polyps with diverticulosis

Figure 2 Endoscopic ultrasonographic examination of early minimal lesion (A) and advanced lesion (B) showing thickening of the first and second layers (mucosa) and irregular echoic lesion in the third layer (submucosa) with hypertrophy of the fourth layer (muscularis propria), and irregular low echoic lesion throughout colonic wall, respectively.